Global populations are aging, for the 1st time in history, we have more people > 64 than we have children < 5. Scientists attempting to slow/reverse aging aren't typically focusing on increasing lifespans, but on increasing healthspans, life spent free of disease Research in animals suggests that targeting aging is far more efficient than treating diseases one at a time. Traditionally, aging biology has been ignored in mainstream medical research. Why is aging biology research important for healthcare?Īge is the largest risk factor for many chronic diseases like Alzheimer's, stroke, and cancer. The potential anti-ageing effects of PCC1 demonstrated in our preclinical assays provide good support for further translational and clinical development of PCC1, with the overall aim of achieving a longer and healthier life. ![]() This is unique to medicines that target aging.Īltogether, our study opens a new avenue for extending healthspan and prolonging lifespan and treating age-related pathologies with a senotherapeutic agent (with both senomorphic and senolytic potential), which is derived from natural sources and possesses pronounced efficacy. Aging leads to multiple chronic diseases, so slowing aging delays the onset of all chronic diseases, simultaneously. Increased survival is important because it suggests that aging is delayed and/or partly reversed. grip strength, walking speed), and enhanced anti-cancer response to chemotherapy, and more importantly increased survival. The authors show evidence of improvements in multiple health parameters - increased physical health (e.g. This paper investigates PCC1 derived from grape seed extract, finding that it can be used as a senolytic drug capable of clearing senescent cells that accumulate throughout the body with aging. Clearing these aged cells extends healthy lifespan in mice by making them younger. Senescent cells accumulate with age, driving multiple chronic diseases like cancer, atherosclerosis, and Alzheimer's. New to reddit? Click here! Get flair in /r/science Previous Science AMA's Repeat or flagrant offenders will be banned.Comments dismissing established findings and fields of science must provide evidence.Criticism of published work should assume basic competence of the researchers and reviewers.Non-professional personal anecdotes will be removed.No off-topic comments, memes, low-effort comments or jokes.All submissions must have flair assigned.No blogspam, images, videos, or infographics.Research must be less than 6 months old.No editorialized, sensationalized, or biased titles.No summaries of summaries, re-hosted press releases, or reposts.Directly link to published peer-reviewed research or media summary. ![]() I receive a small commission on qualifying purchases. Post contains affiliate links as a service to my readers. Try a little bit first to see that it works, especially relevant for the food spray of course. I am sure there are many more uses for the product, but as with all products that are used in your home, exercise caution. ![]() Put the cap on, shake it up and spray as needed. In an average 32 ounce spray bottle, fill with water and add 20 drops of grapefruit seed extract. If your sink is full of dishes, and you don’t have the time to clean them up, you can turn the grapefruit seed extract into a spray and use it like the commercial spray washes available at most grocery stores. Put the food items you need to wash, in the water and let them soak for a brief time. It is a lot cheaper than buying a prepared sprays in stores.įill up your sink with water and add about 35 drops of grapefruit seed extract, while the sink is filling.
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